June 28, 2025

We’re giving the classic Negroni a bold new twist with mezcal, and it might just become your new favorite. If you’ve been looking for a mezcal negroni cocktail recipe that’s simple, flavorful, and a little unexpected, you’re in the right place. The original Negroni was born in early 1900s Florence when Count Camillo Negroni asked for a stronger version of his Americano. That request led to a mix of gin, sweet vermouth, and Campari, and it quickly became a classic.

mezcal negroni cocktail recipe

Now we’re swapping out the gin for mezcal. The equal-parts ratio makes this drink easy to build, and mezcal adds a smoky, earthy depth that brings something new to the table. It’s still a Negroni, just with a bold edge.

In this post, we’ll walk you through the basics, help you pick the right mezcal, suggest some vermouth pairings, and share a few creative finishing touches. If you’re in the mood to shake things up, this Mezcal Negroni is a great place to start.

What You'll Need to Make a Mezcal Negroni

Let’s break down everything we use to make a great Mezcal Negroni. From the spirits to the tools, each part plays a role in how the drink turns out. When we choose the right ingredients and keep things simple behind the bar, the whole process feels easy and enjoyable.

Ingredients and Substitutions

  • Mezcal – We usually go with joven mezcal for its clean, smoky flavor that doesn’t overpower the drink. If we’re in the mood for something bolder, reposado adds more depth. Our favorites are Montelobos and Del Maguey because they bring great flavor without stretching the budget.
  • Campari – This gives the drink its classic bitter bite. Want to switch things up? Gran Classico offers a softer flavor, Cynar adds a herbal twist, and Leopold Bros Aperitivo brings something a little different.
  • Sweet Vermouth – This ties everything together. Carpano Antica brings bold richness, Cocchi di Torino has a fruitier, lighter profile, and Dolin keeps it crisp and clean. Taste matters here, so don’t be afraid to try a few.
  • Orange Twist – It’s not just a garnish. It adds brightness and balance to the drink. We twist the peel over the glass to release the oils. If you want to add a little flair, warm the peel near a flame for a quick burst of citrus aroma.

You might also like: 18 Best Vermouth Cocktails

Equipment You’ll Need

You don’t need a fancy setup to make a great Mezcal Negroni. Just a few basics will do the trick.

  • Mixing glass
  • Bar spoon
  • Strainer
  • Rocks glass or coupe glass
  • Jigger
  • Peeler or small knife

If you’re just starting to build your home bar, we’ve put together a quick guide to the essential bar tools that covers everything you need.

How to Make a Mezcal Negroni Cocktail

Making a Mezcal Negroni is easy, and that’s part of what makes it such a go-to for us. We stick with equal parts mezcal, Campari, and sweet vermouth. No need to complicate it.

We stir everything over ice in a mixing glass for about 30 seconds. Stirring keeps the texture smooth and blends the flavors without adding bubbles. Once it’s well chilled, we strain it into a glass over fresh ice.

When it comes to glassware, we usually reach for a classic rocks glass. But if we’re in the mood for something a little more stylish, we love using the Whiskey Wobble rotating glass. It adds a bit of flair and makes the experience feel more special.

To finish it off, we grab a strip of orange peel, hold it over the drink, and give it a firm twist so the oils hit the surface. Then we drop it in as a garnish for a fresh, citrusy touch.

If you ever want to check the measurements or follow along, you’ll find the full recipe in the card below.

Tips and Tricks to Make the Best Mezcal Negroni Cocktail

  • Use fresh, chilled vermouth – We always keep our vermouth in the fridge. Warm or old vermouth can throw off the drink, so keeping it cold helps everything taste crisp and balanced.
  • Pick the right mezcal – We like something rich and smooth, but not too smoky unless we’re going for a bold kick. Montelobos and Alipus are two of our favorite bottles that work well in this cocktail.
  • Flame the orange peel for extra aroma – Want to level it up? Warm the peel near a lighter and squeeze it over the drink. This releases a burst of citrus oil and gives the cocktail a fragrant finish.
  • Adjust the ratios to your taste – Everyone has a different idea of what makes the perfect Negroni. Try a few of these ratios and see what hits just right:
    • Classic – 1 mezcal, 1 vermouth, 1 Campari
    • Stronger – 1.5 mezcal, 1 vermouth, 1 Campari
    • Smoother – 1 mezcal, 1.5 vermouth, 1 Campari

Mezcal Negroni Variations to Try

One of the best parts about mixing drinks at home is experimenting with new flavors. Here are a few of our favorite ways to change up the classic Mezcal Negroni:

  • Spicy Mezcal Negroni – We add a dash of chili tincture just before serving. It gives the drink a smoky, spicy kick that pairs perfectly with mezcal’s bold flavor.
  • Blanco Tequila Negroni – Swapping mezcal for blanco tequila makes the drink lighter and more citrusy. It’s crisp, clean, and a great option when we want something a little brighter.
  • White Negroni with Mezcal – Instead of Campari, we use Suze or another gentian liqueur. This version has a bittersweet edge and a golden hue that feels extra refreshing. It’s one of our favorite picks for summer.
  • Aged Mezcal Negroni – Using reposado mezcal adds soft oak notes and a hint of vanilla. It smooths out the drink and brings a rich, slightly sweeter finish.

Trying new combinations like these keeps our mezcal negronis exciting and always a little unexpected.

Related: What’s the Difference Between Tequila and Mezcal?

Love Mezcal? Try These Next

If you’re into bold flavor like we are, mezcal has way more to offer beyond the Negroni. Here are a few of our favorite mezcal cocktails that keep things fresh, smoky, and seriously fun to make.

  • Mezcal Margarita – We swap in mezcal for tequila to give this classic a smoky twist that still feels familiar.
  • Oaxaca Old Fashioned – This one blends mezcal with reposado tequila for a smooth, spicy upgrade to the original.
  • Mezcal Paloma – Tart grapefruit juice and mezcal come together for a bright, refreshing cocktail that’s perfect on a warm day.
  • Naked & Famous – A balanced mix of mezcal, Aperol, and yellow Chartreuse that’s colorful, bold, and surprisingly easy to sip.
  • Mezcal Sour – Lime juice and egg white give this one a tangy kick and a creamy, frothy texture we can’t get enough of.

If you’re ready to explore more, these cocktails are a great place to start. Mezcal has a way of turning simple drinks into something unforgettable, and there’s always room to find a new favorite.

Frequently Asked Questions

What is the difference between a Negroni and a Mezcal Negroni?

A classic Negroni uses gin, while a Mezcal Negroni swaps in mezcal for the spirit. Gin brings a crisp and herbal taste, while mezcal adds smoke, earth, and a bolder edge. We get a new flavor twist that appeals to fans of smoky drinks and anyone seeking something a bit richer.

What mezcal is best for a Negroni?

For our Mezcal Negroni, joven mezcal works best because it’s clear, smooth, and not aged. We recommend brands like Del Maguey Vida, Montelobos, or El Silencio for a flavor that blends well but does not overpower. More complex, aged mezcals are often best enjoyed neat.

What’s the best sweet vermouth for a Mezcal Negroni?

Top picks for sweet vermouth are Carpano Antica (rich and vanilla), Cocchi Vermouth di Torino (smooth), Punt e Mes (extra bitter), and Dolin (light). We should keep our vermouth in the fridge once it is open, and drink it within a month. The choice changes the drink’s sweetness and bitterness, so pick what fits our tastes.

Can I batch a Mezcal Negroni for a party?

We can batch Mezcal Negronis by mixing equal parts mezcal, Campari, and sweet vermouth with a bit of water. The batch should be kept cold in the fridge or served over plenty of ice from a large pitcher. It’ll keep for a few days if chilled, and we can prep garnishes and glasses ahead to speed things up.

What is the alcohol content of a Mezcal Negroni?

The average Mezcal Negroni contains about 21 to 23 percent alcohol by volume. This puts it on par with classic, spirit-forward cocktails like the Old Fashioned. Each serving packs a good punch, so it’s not a light drink.

How strong is a Mezcal Negroni?

Mezcal Negronis are strong, slow-sipping cocktails meant to be enjoyed with care. Stirring with ice chills and slightly dilutes the mix, but we still get plenty of alcohol. With a typical serving size around three ounces, it’s best enjoyed at a steady pace.

mezcal negroni cocktail recipe

Mezcal Negroni Recipe

The Mezcal Negroni is our smoky spin on a classic, blending bitter, sweet, and earthy flavors in a bold and balanced mix. Its deep red color and crisp finish make it just right for happy hour or a late-night sip.
Prep Time 5 minutes
Total Time 5 minutes
Course Cocktails, Drinks
Cuisine American
Servings 1

Equipment

  • Mixing Glass
  • Bar Spoon
  • Strainer
  • Rocks glass or Whiskey Wobble rotating glass
  • Jigger
  • Peeler or small knife

Ingredients
  

  • 1 oz mezcal
  • 1 oz sweet vermouth
  • 1 oz Campari
  • Orange twist or half-wheel for garnish

Instructions
 

  • Pour mezcal, sweet vermouth, and Campari to a mixing glass filled with ice
  • Stir for about 30 seconds until the drink is cold and well mixed
  • Strain into a rocks glass over a large ice cube or into a chilled coupe glass
  • Twist an orange peel over the drink to release the oils, then drop it in or rest it on the rim as garnish
Keyword 3 ingredient cocktail, campari cocktail, mezcal cocktails, mezcal negroni cocktail recipe
About the Author The Drinks Daddy

Meet Lance, the intrepid founder of DrinksDaddy.com. Stepping out from a tradition where spirits were once taboo, Lance has embraced his passion for mixology with open arms and a shaker in hand. Lance’s journey from an ex-Mormon to a mixology enthusiast is as unique as the drink recipes he curates—each one tells a story of discovery and delight.

Lance doesn't hail from a line of bartenders or boast a resume of mixology certificates. Instead, he brings a fresh perspective to the craft, armed with curiosity, a penchant for innovation, and a helping hand from artificial intelligence like ChatGPT. His approach is grounded in the belief that the best way to learn is by doing—and, of course, tasting.

Whether he's deconstructing the classics or inventing a new cocktail craze, Lance is all about making mixology accessible and enjoyable. At DrinksDaddy.com, he invites you to join in as he shakes, stirs, and toasts to the endless possibilities that await in every glass. So grab your favorite libation, and let's raise a glass to Lance, who's here to prove that the art of the perfect cocktail is just a pour away. Welcome to the DrinksDaddy.com family, where the spirit of exploration turns every visitor into a mixology maestro. Here's to the delicious adventures ahead!

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